The integrity of chemically treated plasmid DNA as a chemical-based choice for prion clearance

In regenerative medical merchandise for medical purposes, a significant concern is the danger of ruminant-derived supplies creating transmissible spongiform encephalopathy (TSE) within the manufacturing course of. Due to the danger of TSE inflicting prion illness, the uncooked supplies derived from ruminants ought to be compliant with the “Customary for Organic Uncooked Supplies” to make sure the standard and security of pharmaceutical merchandise.

We due to this fact examined whether or not plasmid DNA may face up to 4 chemical reagents (Gdn-HCl, Gdn-SCN, TCA, or SDS), having referred to the report by Tateishi et al. [1], which describes how Creutzfeldt-Jakob illness pathogens will be inactivated by chemical reagents able to producing a 7-log discount in prion inactivation. We noticed that plasmid DNA was combined with chemical reagents and that the performance of plasmid DNA was equal for each chemical and non-chemical remedy.

The efficiency of plasmid DNA was monitored by the existence of DNA fragments and the perform by which GFP proteins had been produced by HEK293-cell transfected plasmid DNA. The existence of DNA fragments was detected in plasmid DNA handled by chemical reagents, besides when present process TCA remedy. Moreover, when HEK293 cells had been transfected with the plasmid DNA after chemical remedy, GFP protein was produced. These outcomes point out that plasmid DNA can face up to the chemical therapies for blocking prion transmission.

Identification of a Potential Membrane-Concentrating on Sequence within the C-Terminus of the F Plasmid Segregation Protein SopA

Steady upkeep and partitioning of the ‘Fertility’ plasmid or the F plasmid in its host Escherichia coli require the perform of a ParA superfamily of proteins often called SopA. The mechanism by which SopA mediates plasmid segregation is effectively studied. SopA is a nucleoid-binding protein and binds DNA in an ATP-dependent however sequence non-specific method. ATP hydrolysis stimulated by the binding of the SopBC complicated mediates the discharge of SopA from the nucleoid.

Cycles of ATP-binding and hydrolysis generate an ATPase gradient that strikes the plasmid by a chemophoresis pressure. Nucleoid binding of SopA thus assumes a central function in its plasmid-partitioning perform. Nevertheless, earlier work additionally means that the F plasmid will be partitioned into anucleate cells, thus implicating nucleoid impartial partitioning. Curiously, SopA can be reported to be related to the inside membrane of the micro organism. Right here, we report the identification of a doable membrane-targeting sequence, a predicted amphipathic helix, on the C-terminus of SopA.

Molecular dynamics simulations point out that the anticipated amphipathic helical motif of SopA has weak affinity for membranes. Furthermore, we experimentally present that SopA can affiliate with bacterial membranes, is detectable within the membrane fractions of bacterial lysates, and is delicate to the membrane potential. Additional, not like the wild-type SopA, a deletion of the C-terminal 29 amino acids leads to the lack of F plasmids from bacterial cells.

The integrity of chemically treated plasmid DNA as a chemical-based choice for prion clearance

Novel lipid mixture for supply of plasmid DNA to immune cells within the spleen

This research experiences on the event of a novel lipid mixture that allows the environment friendly and extremely selective supply of plasmid DNA (pDNA) to immune cells within the spleen. Utilizing DODAP, an ionizable lipid that was beforehand considered inefficient for gene supply, we present for the primary time, that this ignored lipid will be efficiently used for environment friendly and focused gene supply in vivo, however solely when mixed with DOPE, a particular helper lipid. Utilizing sure DODAP and DOPE ratios resulted within the formation of lipid nanoparticles (LNPs) with a ~ 1000-fold increased gene expression, and this expression was particular for the spleen, making it essentially the most spleen-selective system for transfection utilizing pDNA.

The developed DODAP/DOPE-LNPs to focus on immune cells within the spleen through receptors for complement C3 and this pathway is essential for environment friendly gene expression. We hypothesize that the excessive spleen transfection exercise of DODAP/DOPE-LNPs is attributable to the promotion of gene expression related to B cell activation through complement receptors.

LNPs encapsulating tumor-antigen encoding pDNA confirmed each prophylactic and therapeutic anti-tumor results. The optimized LNPs resulted within the manufacturing of various cytokines and antigen-specific antibodies in addition to exerting antigen-specific cytotoxic results. This research revives using DODAP in gene supply and highlights the significance of utilizing applicable lipid mixtures for delivering genes to particular cells.

Dilemma on plasmid DNA purification: binding capability vs selectivity

Plasmid DNA chromatography is a robust discipline in fixed improvement and evolution. The usage of this system is taken into account necessary within the manufacturing of an environment friendly and protected formulation to be utilized for plasmid-mediated gene remedy. Regarding this, the seek for a really perfect chromatographic assist/ligand mixture motivated scientist to pursue a steady enchancment on the plasmid chromatography efficiency, in search of a development on the ligands and helps used.

miRNA Isolation Kit
FAMIK--001 Rxns: 100
EUR 398.4
Description: Contents of the kit:
  • Rxns:100Lysis
  • Buffer-10 ml
  • Acid-Phenol-10 ml
  • RNA Column and Collection Tube-100 sets
  • Wash Buffer-10 ml
  • Release Buffer-0.5 ml

miRNA Isolation Kit
FAMIK--002 Rxns: 50
EUR 267.6

Mitochondria Isolation Kit
AR0156 1 kit
EUR 127.2

MicroRNA Isolation Kit
KS341025 1 kit
EUR 307.2
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

miRNA Isolation Kit
FYG304-100P 100 Preps Ask for price

Rna Isolation Kit
11828665001 EACH
EUR 330.6

Microsome Isolation Kit
K249-50 each
EUR 633.6

Preadipocyte Isolation Kit
K583-5 each
EUR 639.6

Apoptotic Cell Isolation Kit
55R-1349 30 units
EUR 874.8
Description: Apoptotic Cell Isolation Kit for use in the research laboratory

Mitochondrial DNA Isolation Kit
55R-1361 50 assays
EUR 990
Description: Mitochondrial DNA Isolation Kit for use in the research laboratory

Genomic DNA Isolation Kit
55R-1362 50 assays
EUR 462
Description: Genomic DNA Isolation Kit for use in the research laboratory

Cell Mitochondria Isolation Kit
abx090630-50100tests 50-100 tests
EUR 309.6

Tissue Mitochondria Isolation Kit
abx090631-50100assays 50-100 assays
EUR 309.6

Lipid Droplet Isolation Kit
MET-5011 50 preps
EUR 498
Description: Lipid droplets are lipid rich organelles found in the adipose tissue of eukaryotes. They function to regulate the hydrolysis and storage of neutral lipids and serve as storage for cholesterol and acyl-glycerols. Lipid droplets have also been associated with inflammatory responses, obesity, atherosclerosis, and cancer.

Easy3-RNA Isolation Kit
FYG501-100P 100 Preps Ask for price

Easy3-RNA Isolation Kit
FYG501-500P 500 Preps Ask for price

Serum DNA Isolation Kit
K5018100 1 kit
EUR 432

Saliva DNA Isolation Kit
K5011050 1 kit
EUR 307.2

Urine DNA Isolation Kit
K5011150 1 kit
EUR 307.2

Stool DNA Isolation Kit
K5011250 1 kit
EUR 307.2

Cartilage RNA Isolation Kit
K2031010 1 kit
EUR 502.8
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Mitochondrial DNA Isolation Kit
K2117-50 50 assays
EUR 718.8

Genomic DNA Isolation Kit
K2118-50 50 assays
EUR 385.2

Total RNA Isolation Kit
P-9100 50 samples
EUR 416.7

ExoPure? Isolation Kit   (Urine)
K1240-10 each
EUR 836.4

ExoPure? Isolation Kit   (Urine)
K1240-2 each
EUR 483.6

Apoptotic Cell Isolation Kit
K258-30 each
EUR 561.6

Yeast Mitochondria Isolation Kit
K259-50 each
EUR 502.8

Mitochondrial DNA Isolation Kit
K280-50 each
EUR 705.6

Genomic DNA Isolation Kit
K281-50 each
EUR 326.4

Yeast Nuclei Isolation Kit
K289-50 each
EUR 470.4

Lipopolysaccharide (LPS) Isolation Kit
K438-10 each
EUR 333.6

Frit Kit
FRIT-KIT 1each
EUR 148.8
Description: Kit to create frits in capillaries. Includes formamide, Kasil-1, Kasil-1624 and a cleaving tool.

Column Packing Kit
PACK-KIT 1pack
EUR 1242
Description: Column packing kit for pressure cells. Includes: HPREG regulator, TBNG10 tubing, CAP-75 capillary, and STRB5X2 stir bar.

Rapid Bacteria RNA Isolation Kit
BS8625 50Preps
EUR 95.63

Rapid Blood RNA Isolation Kit
BT4182 10Preps
EUR 98.36

Rapid Blood RNA Isolation Kit
BT4183 50Preps
EUR 197.03

Rapid Blood RNA Isolation Kit
BT4184 250preps
EUR 608.1

Circulating Nuleic Acid Isolation Kit
FACFK-050 50 preps
EUR 589.2

Circulating Nuleic Acid Isolation Kit
FACFK-100 100 preps
EUR 990

Total RNA Isolation Kit II
FATRS--001 100 preps
EUR 369.6

Total RNA Isolation Kit II
FATRS--050 50 preps
EUR 259.2

Exo-Urine EV Isolation Kit
EXOU100A-1 2 x 5 reactions
EUR 661.2

Easy3-Plant RNA Isolation Kit
FYG502-100P 100 Preps Ask for price

Easy3-Plant RNA Isolation Kit
FYG502-500P 500 Preps Ask for price

Easy3-Total NucleicAcid Isolation Kit
FYG504-100ML 100 ml Ask for price

Easy3-Total NucleicAcid Isolation Kit
FYG504-500ML 500 ml Ask for price

Genoirse Plant DNA Isolation Kit
GR101083 50
EUR 267.6

Apoptotic DNA Ladder Isolation Kit
K2045-50 50 assays
EUR 602.4

Rapid Plant RNA Isolation Kit
PT4191 50Preps
EUR 95.63

FitAmp Urine DNA Isolation Kit 
P-1017-050 50 Samples
EUR 171.6

FitAmp Urine DNA Isolation Kit 
P-1017-100 100 Samples
EUR 292.6

ChromaFlash Chromatin Isolation & Shearing Kit 
P-2023-100 100 Preparations
EUR 189.2

XCF Exosomal DNA Isolation Kit
XCF200A-1 20 rxn
EUR 463.2

FitAmp Gel DNA Isolation Kit
P-1007 100 Samples
EUR 324.48

FitAmp Urine DNA Isolation Kit 
P-1017
  • EUR 474.12
  • EUR 171.60
  • EUR 292.60
  • 100 Samples
  • 50 Samples
  • 100 Samples

ChromaFlash Chromatin Isolation & Shearing Kit 
P-2023
  • EUR 324.48
  • EUR 189.20
  • 100 Preperations
  • 100 Preparations

Total RNA Isolation Kit (Tissue)
P-9102 50 samples
EUR 416.7

Total RNA Isolation Kit (Plant)
P-9104 50 samples
EUR 416.7

EpiMag Viral RNA Isolation Kit
P-9108-050 50 samples
EUR 152.9

EVery EV RNA Isolation Kit
EVery100B-1 20 preps
EUR 412

ExoPure? Isolation Kit   (Cell Media)
K1237-10 each
EUR 796.8

ExoPure? Isolation Kit   (Cell Media)
K1237-2 each
EUR 470.4

ExoPure? Isolation Kit   (Serum, Plasma)
K1238-10 each
EUR 836.4

ExoPure? Isolation Kit   (Serum, Plasma)
K1238-2 each
EUR 470.4

ExoPure? Isolation Kit   (Bio Fluids)
K1241-10 each
EUR 836.4

ExoPure? Isolation Kit   (Bio Fluids)
K1241-2 each
EUR 483.6

Apoptotic DNA Ladder Isolation Kit
K170-50 each
EUR 561.6

EZExtract? Core Histone Isolation Kit
K234-100 each
EUR 314.4

Cell Surface Protein Isolation Kit
K295-10 each
EUR 601.2

Bacterial Genomic DNA Isolation Kit
K309-100 each
EUR 451.2

OrgFrontier? Plasma Membrane Isolation Kit
K414-10 each
EUR 679.2

Org Frontier? Chloroplast Isolation Kit
K468-10 each
EUR 666

Whole Blood DNA Isolation Kit
K528-100 each
EUR 451.2

CD19 Positive Cell Isolation Kit
78564-1 1 x 10^8 Cells
EUR 70
Description: The CD19 Positive Cell Isolation Kit is designed to magnetically separate CD19-expressing-cells from a complex immune cell population. This kit is optimized for the isolation of CD19 positive cells from normal human peripheral blood mononuclear cells (PBMCs). Cells are incubated with the antibody:bead complex and placed on a magnet for quick and easy separation. When placed on the magnet, CD19-positive cells will be immobilized along the side of the tube while undesired CD19-negative cells will remain in suspension for easy removal.

CD19 Positive Cell Isolation Kit
78564-2 1 x 10^9 Cells
EUR 630
Description: The CD19 Positive Cell Isolation Kit is designed to magnetically separate CD19-expressing-cells from a complex immune cell population. This kit is optimized for the isolation of CD19 positive cells from normal human peripheral blood mononuclear cells (PBMCs). Cells are incubated with the antibody:bead complex and placed on a magnet for quick and easy separation. When placed on the magnet, CD19-positive cells will be immobilized along the side of the tube while undesired CD19-negative cells will remain in suspension for easy removal.

PCR Mycoplasma Detection Kit
M034-Kit Kit
EUR 319.2

PSEUDOMONAS ISOLATION AGAR
P16-114-10kg 10 kg
EUR 2058

PSEUDOMONAS ISOLATION AGAR
P16-114-2kg 2kg
EUR 494.4

PSEUDOMONAS ISOLATION AGAR
P16-114-500g 500 g
EUR 177.6

PSEUDOMONAS ISOLATION BROTH
P16-115-10kg 10 kg Ask for price

PSEUDOMONAS ISOLATION BROTH
P16-115-2Kg 2 Kg Ask for price

PSEUDOMONAS ISOLATION BROTH
P16-115-500g 500 g Ask for price

Cas9 Protein and T7 gRNA SmartNuclease Synthesis Kit
CAS400A-KIT 1 kit (10 rxn)
EUR 1332

Pesticide Kit Containing All 10 Multi-Compound Mixes
SPXPR-KIT 1ML
EUR 1923.18

Cas9 Protein and T7 gRNA SmartNuclease Synthesis Kit
CAS410A-KIT 1 kit (10 rxn)
EUR 798

Cas9-EGFP Protein and T7 gRNA SmartNuclease Synthesis Kit
CAS420A-KIT 1 kit (10 rxn)
EUR 828

Multiplex gRNA Kit + EF1-T7-hspCas9-H1-gRNA linearized SmartNuclease vector
CAS700A-KIT 10 rxn
EUR 1358.4

Multiplex gRNA Kit + CAG-T7-hspCas9-H1-gRNA linearized SmartNuclease vector
CAS720A-KIT 10 rxn
EUR 1358.4

Multiplex gRNA Kit + CMV-T7-hspCas9-H1-gRNA linearized SmartNuclease vector
CAS740A-KIT 10 rxn
EUR 1358.4

FastPure Bacteria DNA Isolation Mini Kit
DC103 100 rxn
EUR 212.4

FastPure Plant DNA Isolation Mini Kit
DC104 50 rxn
EUR 192

FastPure FFPE DNA Isolation Mini Kit
DC105 50 rxn
EUR 241.2

Rapid Bacteria Genomic DNA Isolation Kit
BS8225 50Preps
EUR 91.97

Soil DNA Isolation Mini Kit (50prep)
FASOI-001 50 preps
EUR 189.6

Soil DNA Isolation Mini Kit (100prep)
FASOI-001-1 100 preps
EUR 241.2

Soil DNA Isolation Midi Kit (24prep)
FASOI-002 24 preps
EUR 259.2

Soil RNA Isolation Mini Kit (50prep)
FASRK-001 50 preps
EUR 180

Soil RNA Isolation Mini Kit (100prep)
FASRK-100 100 preps
EUR 224.4

Mammalian Mitochondria Isolation Kit for Tissue
abx098857-50rxns 50 rxns
EUR 493.2

Rapid Fungal Genomic DNA Isolation Kit
FT71415 50Preps
EUR 91.97

Easy3-Plant Genomic DNA Isolation Kit
FYG503-100P 100 Preps Ask for price

Easy3-Plant Genomic DNA Isolation Kit
FYG503-500P 500 Preps Ask for price

Broad Range Total RNA Isolation Kit
K1341050 1 kit
EUR 319.2
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Blood and Serum DNA Isolation Kit
K5017100 1 kit
EUR 432

FitAmp Plasma/Serum DNA Isolation Kit 
P-1004-1 50 Samples
EUR 149.6

FitAmp Plasma/Serum DNA Isolation Kit 
P-1004-2 100 Samples
EUR 253

MagIso CD3 Cell Isolation Kit, Mouse
WHK-B009 20 tests, 200 tests Ask for price

MagIso CD90.2 Cell Isolation Kit, Mouse
WHK-B010 20 tests, 200 tests Ask for price

MagIso Neutrophil Cell Isolation Kit, Mouse
WHK-B015 10 tests, 100 tests Ask for price

MagIso CX3CR1 Cell Isolation Kit, Mouse
WHK-B017 10 tests, 100 tests Ask for price

MagIso NK Cell Isolation Kit, Human
WHK-B023 20 tests, 200 tests Ask for price

Methylamp Coupled DNA Isolation & Modification Kit
P-1002 40 Samples
EUR 474.12

FitAmp Plasma/Serum DNA Isolation Kit 
P-1004
  • EUR 416.70
  • EUR 149.60
  • EUR 253.00
  • 100 Samples
  • 50 Samples
  • 100 Samples

EpiQuik Total RNA Isolation Fast Kit
P-9105-050 50 samples
EUR 176

EpiQuik Magbeads Quick RNA Isolation Kit
P-9106-050 50 samples
EUR 163.9

EpiQuik Viral RNA Isolation Fast Kit
P-9107-050 50 samples
EUR 167.2

ExoPure? Isolation Kit   (Stem Cell Media)
K1239-10 each
EUR 901.2

ExoPure? Isolation Kit   (Stem Cell Media)
K1239-2 each
EUR 510

Plant Tissue Genomic DNA Isolation Kit
K316-100 each
EUR 451.2

Human Whole Blood Monocyte Isolation Kit
K933-30 each
EUR 451.2

Mammalian Cell Genomic DNA Isolation Kit
K967-100 each
EUR 457.2

T7 gRNA SmartNuclease Synthesis Kit (includes CAS510A-1 & T7 IVT synthesis reagents)
CAS510A-KIT 1 Kit
EUR 966

Multiplex gRNA Kit + Cas9 Nickase: EF1-T7-hspCas9-nickase-H1-gRNA linearized SmartNickase vector
CAS750A-KIT 10 rxn
EUR 1358.4

Multiplex gRNA Kit + Cas9 Nickase: CAG-T7-hspCas9-nickase-H1-gRNA linearized SmartNickase vector
CAS770A-KIT 10 rxn
EUR 1358.4

Multiplex gRNA Kit + Cas9 Nickase: CMV-T7-hspCas9-nickase-H1-gRNA linearized SmartNickase vector
CAS790A-KIT 10 rxn
EUR 1358.4

Cas9 SmartNuclease Extra Ligation Kit [includes 5x ligation buffer (10 ul) and Fast ligase (2.5ul)]
CAS9LIG-KIT 1 Kit
EUR 183.6

Claritas PPT Grade Minerals Testing Kit for ICP-MS 1000 ug/mL (1000 ppm) 6 each 30mL
SPXMT-KIT 30ML
EUR 237.12

PinPoint-FC 293T Platform Kit for Targeted Gene Insertion (includes PIN320A-1, PIN200A-1, PIN510A-1 & PIN600A-1)
PIN320A-KIT 1 Kit
EUR 5929.2

Claritas PPT Grade Heavy Metals Testing Kit for ICP-MS 1000 ug/mL (1000 ppm) 6 each 30mL
SPXHM-KIT 30ML
EUR 245.1

PinPoint-FC Murine iPSC Platform Kit for Targeted Gene Insertion (includes PIN340iPS-1, PIN200A-1, PIN510A-1 & PIN600A-1)
PIN340iPS-KIT 1 Kit
EUR 5929.2

cfMAX cfDNA Isolation System
CFMAX100A-1 1 Kit
EUR 574.8

Albumin, cold alcohol isolation
A0903 1g
EUR 99.67

RNA-easy Isolation Reagent
R701-01 100 ml
EUR 201.6

RNA-easy Isolation Reagent
R701-02 200 ml
EUR 254.4

Kinesis Rheodyne Isolation Seal
CHR2645 EACH
EUR 21.66

Kinesis Rheodyne Isolation Seal
CHR2791 EACH
EUR 37.62

10x Cell Isolation Buffer
78563 5 ml
EUR 25
Description: This buffer is intended for use with mammalian cells during magnetic cell isolation or single cell processing. This buffer is optimized and formulated to reduce nonspecific binding and cell clumping

FastPure Cell/Tissue DNA Isolation Mini Kit
DC102 100 rxn
EUR 212.4

FastPure Blood DNA Isolation Mini Kit V2
DC111-01 50 rxn
EUR 214.8

FastPure Blood DNA Isolation Mini Kit V2
DC111-02 200 rxn
EUR 472.8

One-Tube Bacteria Genomic DNA Isolation Kit
BS8413 100preps
EUR 94.72

One-Tube Bacteria Genomic DNA Isolation Kit
BS8414 500Preps, 500prep
EUR 198.85

Soil DNA Plus Isolation Mini Kit (50prep)
FAPSO-001 50 preps
EUR 189.6

Soil DNA Plus Isolation Mini Kit (100prep)
FAPSO-001-1 100 preps
EUR 241.2

Mammalian Mitochondria Isolation Kit for Cultured Cells
20-abx098856
  • EUR 126.00
  • EUR 493.20
  • 2 rxns
  • 50 rxns

FastPure Cell/Tissue Total RNA Isolation Kit
RC101 50 rxn
EUR 274.8

FitAmp General Tissue Section DNA Isolation Kit 
P-1003-1 50 Samples
EUR 253

FitAmp General Tissue Section DNA Isolation Kit 
P-1003-2 100 Samples
EUR 490.6

FitAmp Paraffin Tissue Section DNA Isolation Kit 
P-1009-1 50 Samples
EUR 239.8

FitAmp Paraffin Tissue Section DNA Isolation Kit 
P-1009-2 100 Samples
EUR 454.3

EpiQuik Circulating Cell-Free DNA Isolation Kit
P-1064-25 25 Isolations
EUR 148.5

EpiQuik Circulating Cell-Free DNA Isolation Kit
P-1064-50 50 Isolations
EUR 253

MagIso CD4 T Cell Isolation Kit, Human
WHK-B001 10 tests
EUR 724.8

MagIso CD8 T Cell Isolation Kit, Human
WHK-B002 10 tests
EUR 724.8

MagIso CD4 T Cell Isolation Kit, Mouse
WHK-B003 10 tests
EUR 724.8

MagIso CD8 T Cell Isolation Kit, Mouse
WHK-B004 10 tests
EUR 724.8

MagIso Hematopoietic Progenitor Cell Isolation Kit, Mouse
WHK-B005 10 tests
EUR 724.8

MagIso Hematopoietic Progenitor Cell Isolation Kit, Human
WHK-B008 20 tests, 200 tests Ask for price

MagIso Pan Dendritic Cell Isolation Kit, Mouse
WHK-B011 20 tests, 200 tests Ask for price

MagIso Pan B Cell Isolation Kit, Mouse
WHK-B013 20 tests, 200 tests Ask for price

MagIso Hematopoietic Progenitor Cell Isolation Kit, Mouse
WHK-B016 10 tests, 100 tests Ask for price

MagIso Pan Monocyte Cell Isolation Kit, Human
WHK-B021 20 tests, 200 tests Ask for price

MagIso Pan B Cell Isolation Kit, Human
WHK-B022 20 tests, 200 tests Ask for price

MagIso Naïve B Cell Isolation Kit, Human
WHK-B024 20 tests, 200 tests Ask for price

MagIso CD14+ Monocytes Cell Isolation Kit, Human
WHK-B029 10 tests, 100 tests Ask for price

FitAmp General Tissue Section DNA Isolation Kit 
P-1003
  • EUR 754.26
  • EUR 253.00
  • EUR 490.60
  • 100 Samples
  • 50 Samples
  • 100 Samples

FitAmp Paraffin Tissue Section DNA Isolation Kit 
P-1009
  • EUR 702.06
  • EUR 239.80
  • EUR 454.30
  • 100 Samples
  • 50 Samples
  • 100 Samples

EpiMag High Throughput DNA Isolation Universal Kit
P-1022-96 96 Samples
EUR 227.7

EpiQuik Circulating Cell-Free DNA Isolation Kit
P-1064
  • EUR 416.70
  • EUR 148.50
  • EUR 253.00
  • 50 Isolations
  • 25 Isolations
  • 50 Isolations

Human Whole Blood Polymorphonuclear Cell Isolation Kit
K483-30 each
EUR 451.2

AAVS1 Safe Harbor Targeting Vector 2.0 - All-Purpose Donor (AAVS1-SA-puro-MCS), Complete Kit with CAS601A-1 (Cas9 SmartNuclease AAVS1-gRNA Targeting Vector) and GE640PR-1 (Junction PCR Primer Mix to confirm AAVS1 integration site)
GE620A-KIT 1 kit
EUR 2558.4

AAVS1 Safe Harbor Targeting Vector 2.0 - GOI Knock-in Donor (AAVS1-SA-puro-EF1-MCS), Complete Kit with CAS601A-1 (Cas9 SmartNuclease AAVS1-gRNA Targeting Vector) and GE640PR-1 (Junction PCR Primer Mix to confirm AAVS1 integration site)
GE622A-KIT 1 kit
EUR 2558.4

AAVS1 Safe Harbor Targeting Vector 2.0 - Reporter Knock-in Donor (AAVS1-SA-puro-MCS-GFP), Complete Kit with CAS601A-1 (Cas9 SmartNuclease AAVS1-gRNA Targeting Vector) and GE640PR-1 (Junction PCR Primer Mix to confirm AAVS1 integration site)
GE624A-KIT 1 kit
EUR 2558.4

vWF Acty. Kit
ABP-ACT-KIT 12 x 8 microwells
EUR 513.6

vWF Ant. Kit
ABP-TOT-KIT 12 x 8 microwells
EUR 472.8

SmartSEC Single EV Isolation System
SSEC200A-1 10 rxn
EUR 391

Cell Isolation Magnetic Tube Rack
78571 15 ml and 50 ml
EUR 850
Description: This Cell Isolation Magnetic Tube Rack is designed to accompany our magnetic cell isolation products, such as the CD19 Positive Cell Isolation Kit (BPS Bioscience #78564). This magnet can quickly separate cells labeled with magnetic beads and is designed to allow users a near 360° view of their cell samples during separation. This magnet can accommodate both 15 and 50 ml tubes simultaneously, which allows flexibility for scaling up or down your isolation samples. Additionally, the rack is compatible with both conical and round-bottom tubes. The compact nature of this magnet allows it to fit easily in various incubators or refrigerators to match desired conditions.

PrecisionX Multiplex gRNA Cloning Kit
CAS9-GRNA-KIT 10 rxn
EUR 534

CytoSelect Clonogenic Tumor Cell Isolation Kit (5 preps)
CBA-155 5 preps
EUR 957.6
Description: Many solid tumors contain heterogeneous populations of normal and cancerous cells. Separation of these cell populations is key to an accurate assessment of the true genotypic and phenotypic differences between normal and tumor cells. Our CytoSelect Clonogenic Tumor Cell Isolation Kit uses a proprietary semisolid agar medium to facilitate formation of colonies by cells from solid tumors. Colonies are grown in either a 6-well plate or a 35mm culture dish. These colonies are isolated away from single (i.e. normal) cells by size filtration. The viable cells from these colonies can be easily recovered for further analysis.

Mitochondria Isolation Kit for Tissue and Cultured Cells
KC010100 1 kit
EUR 384
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

MagIso Pan B Cell Isolation Kit, Mouse Ⅱ
WHK-B012 20 tests, 200 tests Ask for price

MagIso Natural killer (NK) Cell Isolation Kit, Mouse
WHK-B014 20 tests, 200 tests Ask for price

MagIso CD8 Naïve T Cell Isolation Kit, Mouse
WHK-B018 20 tests, 200 tests Ask for price

MagIso CD4 Naïve T Cell Isolation Kit, Mouse
WHK-B019 20 tests, 200 tests Ask for price

MagIso CD8 Naïve T Cell Isolation Kit, Human
WHK-B025 20 tests, 200 tests Ask for price

MagIso CD8 Memory T Cell Isolation Kit, Human
WHK-B026 20 tests, 200 tests Ask for price

MagIso CD4 Naïve T Cell Isolation Kit, Human
WHK-B027 20 tests, 200 tests Ask for price
The current evaluation explores the totally different approaches used over time to purify plasmid DNA, ambitioning each excessive restoration and excessive purity ranges. Total, it’s introduced a essential dialogue counting on the relevance of the binding capability versus selectivity of the helps.

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